The Shared Resources support the following Research Initiatives
The Excellence Cluster takes an interdisciplinary approach to elucidating the principles of the immune sensory system. In conjunction with experts in classical sensory systems, we aim at resolving the spatiotemporal regulation of sensory input on the receptor level, where clear similarities to classical sensory systems exist.
The Collaborative Research Center 704 is a programme research initiative of the University of Bonn which has been funded by the German Research Foundation (DFG) from January 2006 on. The key objective is to decipher important pathways of local or organ-dependent immune regulation, with particular emphasis on the mechanisms of migration, signalling, cellular activation and the generation of functional repertoires.
All mammalian behavior relies on the recruitment of neuronal ensembles into precisely orchestrated discharges. How the different cellular and synaptic elements of a neuronal ensemble cooperate to produce characteristic patterns of activity in the central nervous system is a fundamental and important question in neuroscience. Resolving the function of elementary synaptic microcircuits that form a more complex circuitry will therefore significantly advance our understanding of brain function.
BIGS Neuroscience is committed to providing a top-level, internationally competitive program in the rapidly developing field of neuroscience. The school is focused on understanding the molecular and cellular mechanisms underlying complex behavior, and the application of these insights to central nervous system disorders. This interdisciplinary school includes scientists from the Faculty of Mathematics and Natural Sciences, the Faculty of Medicine, the German Center for Neurodegenerative Diseases in the Helmholtz Association and the Research Institute Caesar in the Max Planck Association.
Dieser Forschungsverbund dreier Hochschulen befaßt sich mit dem wissenschaftlich und klinisch hoch bedeutsamen Thema “Organfibrosen: Von den Mechanismen der Schädigung zur Beeinflussung der Erkrankung”. Die Forscherinnen und Forscher wenden sich den Fibrosen, der krankhaften Vermehrung von Bindegewebe, in Leber und Niere zu. Derartige Vernarbungen haben häufig einen tödlichen Ausgang und verursachen zudem hohe Behandlungskosten.